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Amphiphilic Structure
The ethyl ether structure provides both water- and oil-phase compatibility for flexible cosmetic formula design.
Stable Vitamin C Derivative
AC-VCE
INCI name: 3-O-Ethyl Ascorbic Acid
CAS No. 86404-04-8
AMPHIPHILIC VITAMIN C DERIVATIVE FOR MODERN SKINCARE
≥98% Assay by HPLC
Amphiphilic
Data-proven Superior Stability
Good Compatibility
Easily Absorbed
Data-Supported Antioxidant Activity
AC-VCE is ANECO 3-O-Ethyl Ascorbic Acid, an amphiphilic vitamin C derivative for brightening and antioxidant skincare formulas. It contains at least 98% 3-O-Ethyl Ascorbic Acid by HPLC and provides solution-stability, tyrosinase-inhibition and DPPH radical-scavenging performance under defined test conditions.
≥98%
Product assay specification by HPLC.
Brightening
Helps reduce tyrosinase activity for brighter-looking skin.
Antioxidant
Provides effective free radical scavenging protection.
Product Identity
AC-VCE Specification Snapshot
Review identity, assay, moisture, pH and melting range before selecting AC-VCE for formulation trials.
| Product Name | AC-VCE | INCI Name | 3-O-Ethyl Ascorbic Acid |
|---|---|---|---|
| Synonym | L-Ascorbic acid, 3-O-Ethyl Ether | CAS No. | 86404-04-8 |
| EC / EINECS No. | 617-849-3 | Molecular Formula | C8H12O6 |
| Molecular Weight | 204.18 g/mol | Appearance | White to off-white crystalline powder |
| Assay by HPLC | ≥98.0% | Moisture | ≤2.0% |
| pH (3% aq.) | 3.0-6.0 | Melting Point | 111.0-116.0°C |
Defined Quality Controls
Assay, moisture, pH, melting point and heavy-metal limits provide defined quality controls.
Practical Cool-Down Addition
For emulsions, dissolve AC-VCE in water and add the solution after the system cools below 45°C.
Stability and Test Context
AC-VCE Stability and Test Conditions
AC-VCE combines at least 98% HPLC assay with solution-stability, DPPH radical-scavenging and tyrosinase-inhibition results under defined test conditions.
| Product Assay | HPLC assay is at least 98.0%; stability retention is evaluated separately. |
|---|---|
| High-Temperature Solution Test | AC-VCE aqueous solution remained visually stable under accelerated storage conditions. |
| 43°C Derivative Comparison | 3-O-Ethyl Ascorbic Acid demonstrated excellent stability compared with other vitamin C derivatives. |
| DPPH Test | Demonstrated strong free radical-scavenging activity in antioxidant evaluation. |
| Finished-Serum Study | Serum containing 3-O-Ethyl Ascorbic Acid showed positive effects in skin and collagen-related evaluations. |
| Recommended Formula pH | pH 4.0-6.0 for formula screening; the 3% aqueous raw-material pH specification is 3.0-6.0. |
Performance
Stability, Radical Scavenging and Tyrosinase Inhibition
50°C solution stability, more than 70% DPPH radical-scavenging capacity and tyrosinase inhibition up to 89.1%.
High-Temperature Stability
More stable than unmodified ascorbic acid.
Tyrosinase Inhibition
Inhibits tyrosinase in both L-tyrosine and L-DOPA oxidation test methods.
Antioxidant Activity
Strong DPPH radical-scavenging capacity.
Amphiphilic Compatibility
Water- and oil-phase compatibility for water-based and emulsion systems.
Application
AC-VCE Application and Processing Guide
Use controlled temperature, pH and dissolution steps to protect AC-VCE during cosmetic formulation.
- Dissolve for single-phase systems Add AC-VCE to the water phase and stir until evenly dissolved.
- Use cool-down addition in emulsions Prepare an AC-VCE aqueous solution separately and add it after the emulsion cools below 45°C.
- Maintain formula pH 4.0-6.0 Adjust and monitor pH during stability work.
- Validate the complete formula Check color, odor, assay retention, packaging, light exposure and compatibility with other actives before scale-up.
Recommended Formula Systems
Brightening serum
Antioxidant essence
Face cream
Lotion
Mask
Ampoule
Uneven skin tone formulas
Anti-aging skincare formulas
Confirm pH, color, assay retention and compatibility in the finished formula before commercial release.
Documents and Support
AC-VCE Technical Documents and Formulation Support
Request the current specification, safety files and supporting test reports before finalizing formula claims.
Product Positioning
Recommended Product Positioning
High-purity, amphiphilic 3-O-Ethyl Ascorbic Acid vitamin C derivative with stability, antioxidant and tyrosinase data for brightening skincare formulas.
Technical Files to Request
Ask for the documents needed for specification review, regulatory review, sample testing and bulk order qualification.
FAQ
AC-VCE FAQ
Answers to common buyer questions about assay, stability, processing, applications and technical documents.
What is AC-VCE used for?
AC-VCE is used in brightening serums, antioxidant essences, creams, lotions, masks, ampoules and uneven skin tone formulas.
What does the ≥98% assay mean?
AC-VCE contains at least 98% 3-O-Ethyl Ascorbic Acid by HPLC. Stability results are stated separately with their temperature, duration, concentration and test method.
How should AC-VCE be added to an emulsion?
Dissolve AC-VCE in a suitable amount of water, then add the solution after the emulsion cools below 45°C. Screen the finished formula at pH 4.0-6.0.
What performance does AC-VCE provide?
AC-VCE remains stable in the stated solution tests, demonstrates potent DPPH radical-scavenging activity, and inhibits tyrosinase in two test methods. Apply each result only within its stated test conditions.
What documents are available for AC-VCE?
Request the current TDS, SDS/MSDS, specification, recent COA sample, stability data, DPPH data, tyrosinase data and regulatory statements.
